Introduction to ATMP Manufacturing webinar

10th December – 4pm

The production of novel advanced therapy medicinal products (ATMPs) contrasts with established biomanufacturing processes for medicines that are synthetically derived (i.e. small molecule drugs) or proteins/peptides expressed by cellular systems (i.e. large molecule biopharmaceuticals). ATMPs present unique bioprocessing challenges such as limited scalability, variable quality of starting material and an inability to sterilize the final product. ATMP developers, clinical teams and patients rely on the provision of high-quality raw materials, effective logistics support, and validated, robust clinical manufacturing processes. This talk will provide a high level overview of how novel cell and gene therapies are produced and discuss some key manufacturing challenges.

Ivan Wall
Ivan Wall
Professor of Regenerative Medicine, Cell & Gene Therapy Bioprocessing
Aston University

Ivanjoined Aston University’s School of Life & Health Sciences in January 2018, having previously been Reader in Cell & Gene Therapy Bioprocessing at University College London (UCL).

He gained his PhD in cell and molecular biology from Cardiff University School of Dentistry in 2006, developing a longstanding interest in why some tissues fail to heal and how stem cells and regenerative medicine might be applied to restore failing tissues and organs. He undertook postdoctoral studies at UCL during 2005-2009 before joining UCL’s Department of Biochemical Engineering, where he established a successful multi-disciplinary research group.

Ivan’s research interfaces cell biology with bioprocessing, biomaterials and novel devices.His work spans fundamental research through to applied and translation studies with industry and clinical collaborators. He has been awarded funding from EPSRC, BBSRC, MRC, Wellcome, Innovate UK, EU, as well as industry. He has played a leading role in successful grant applications totallingover £40M in grant funding, published 70 peer-reviewed papers and is a visiting professor at Dankook University in South Korea. Ivan also coordinates a new MSc programme, Regenerative Medicine Manufacturing, and supervises undergraduate project students and placement students as well as MSc project students.

To find out more about the Advanced therapy education webinar series follow this link